{"id":10913,"date":"2020-07-06T13:54:51","date_gmt":"2020-07-06T20:54:51","guid":{"rendered":"https:\/\/wp.pugetsystems.com\/featured\/case-study-with-dr-adam-glaser-from-the-university-of-washington-247\/"},"modified":"2024-08-16T10:52:32","modified_gmt":"2024-08-16T17:52:32","slug":"case-study-with-dr-adam-glaser-from-the-university-of-washington-247","status":"publish","type":"case_study","link":"https:\/\/www.pugetsystems.com\/featured\/case-study-with-dr-adam-glaser-from-the-university-of-washington-247\/","title":{"rendered":"Case Study with Dr. Adam Glaser from the University of Washington"},"content":{"rendered":"\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Alpenglow&#039;s 3D Spatial Biology Platform - The 3Di\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/1NYM8QY6tck?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"AboutDr_AdamGlaser\">About Dr. Adam Glaser<\/h2>\n\n\n<p>Dr. Glaser works as a researcher in the Molecular Biophotonics Laboratory in the Department of Mechanical Engineering at the University of Washington. He and his team design, fabricate and deploy optical instruments for clinical applications. Specifically, his research over the last 5 years has focused on developing cutting edge light-sheet microscopes for high-throughput 3D imaging.<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"ToolsoftheTrade\">Tools of the Trade<\/h2>\n\n\n<p>The microscopy community is very active and has developed many open-source software packages which is part of Dr. Glaser&#39;s daily workflow.&nbsp; These include Python libraries and hardware drivers for controlling microscopes, and ImageJ \/ FIJI based packages for post processing and visualization of datasets.<\/p>\n\n\n<script type=\"text\/javascript\">\n    jQuery(document).ready(function(){\n        var slid_to = 0;\n        jQuery('#image-gallery-5965').on('slid.bs.carousel', function(e){\n            slid_to = e.to;\n        });\n        jQuery('#image-gallery-5965LargeCarousel').on('slid.bs.carousel', function(e){\n            slid_to = e.to;\n            jQuery('#image-gallery-5965').carousel(slid_to);\n        });\n\n        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data-target=\"#image-gallery-5965LargeCarousel\" data-slide-to=\"2\" ><\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/ol>\n\t\t\t\t\t\t\t\t\t<div class=\"carousel-inner\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"carousel-item active\">\n                                \t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.pugetsystems.com\/pic_disp.php?id=62330&#038;width=900\"\n\t\t\t\t\t\t\t\t     alt=\"Gallery Image\" class=\"d-block mx-auto\" data-id=\"0\" data-toggle=\"modal\" data-target=\"#image-gallery-5965Modal\" \/>\n\t\t\t\t\t\t\t\t\t\n                                \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"carousel-item \">\n                                \t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.pugetsystems.com\/pic_disp.php?id=62331&#038;width=900\"\n\t\t\t\t\t\t\t\t     alt=\"Gallery Image\" class=\"d-block mx-auto\" data-id=\"1\" data-toggle=\"modal\" data-target=\"#image-gallery-5965Modal\" \/>\n\t\t\t\t\t\t\t\t\t\n                                \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"carousel-item \">\n                                \t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.pugetsystems.com\/pic_disp.php?id=62333&#038;width=900\"\n\t\t\t\t\t\t\t\t     alt=\"Gallery Image\" class=\"d-block mx-auto\" data-id=\"2\" data-toggle=\"modal\" data-target=\"#image-gallery-5965Modal\" \/>\n\t\t\t\t\t\t\t\t\t\n                                \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<a class=\"carousel-control-prev\" href=\"#image-gallery-5965LargeCarousel\" role=\"button\" data-slide=\"prev\">\n\t\t\t\t\t\t<span class=\"carousel-control-prev-icon\" aria-hidden=\"true\"><\/span>\n\t\t\t\t\t\t<span class=\"sr-only\">Previous<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<a class=\"carousel-control-next\" href=\"#image-gallery-5965LargeCarousel\" role=\"button\" data-slide=\"next\">\n\t\t\t\t\t\t<span class=\"carousel-control-next-icon\" aria-hidden=\"true\"><\/span>\n\t\t\t\t\t\t<span class=\"sr-only\">Next<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t<\/div><!-- .modal-body -->\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"TechnicalChallenges\">Technical Challenges<\/h2>\n\n\n<p>When asked about the technical challenges he faces, Dr. Glaser said the following:<\/p>\n<p>&quot;Our<a href=\"https:\/\/www.pugetsystems.com\/pic_disp.php?id=62319&amp;width=800&amp;height=800\" rel=\"article_pics noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"img-responsive\" height=\"238\" src=\"https:\/\/www.pugetsystems.com\/pic_disp.php?id=62319&amp;width=350\" style=\"margin: 5px; float: left;\" width=\"242\" \/><\/a> light-sheet microscopes use state-of-the-art scientific CMOS cameras which generate ~1GB of imaging data every second. As a result, there are important considerations for every stage of a datasets&#39; life cycle, including acquisition, transfer, processing, visualization, analysis, and ultimately storage.&quot;<\/p>\n<p>Previously, Dr. Glaser used Dell workstations which were sold by the vendor directly with the high-speed cameras. However, these workstations were limited in terms of CPU\/RAM options, and PCIe slots. This last specification is particularly important, as they use a number of other PCIe cards to control the microscope, including the camera frame grabber. Other PCIe slots support a RAID controller for creating a RAID 0 array to stream the data to a high powered GPU for real-time compression of data, a 10G network card for transferring data to a local server, and a National Instruments card for generating analog voltages.&nbsp;<\/p>\n\n\n<h2 class=\"wp-block-heading\" id=\"PugetSystems\\'Solution\">Puget Systems&#8217; Solution<\/h2>\n\n\n<p>A colleague at the University of Washington initially recommended Puget Systems as a possible solution. After reviewing the custom workstation options, the combination of performance, price point, and customer service was unbeatable at Puget Systems.<\/p>\n<p>Dr. Glaser had a dataset and workflow that benefited by outfitting a workstation with Intel Xeon W-2145 3.7GHz 8-core CPU along with 16GB of ECC RAM and 1TB M.2 SSD drive. Puget Systems pre-wired the workstation for an NVIDIA Titan GPU Dr. Glaser already owned. Unlike the previous vendor, Puget Systems was able to customize a solution that met the needs of Dr. Glaser and the tasks he performs each day. That included a choice of CPU, various RAM options, and a motherboard that gave him extra PCI-e slots for future expansion.<\/p>\n\n<blockquote class=\"puget-blockquote blockquote-blue\">\n    <div class=\"blockquote-text\">\n\t    <p>The customization and high-performance options from Puget Systems were ideal for our needs.<\/p>\n    <\/div>\n        <\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color wp-elements-d79b16f2abe223d761a69b955bbb3461\" id=\"h-talk-to-an-expert\" style=\"color:#130c64\">Talk to an Expert<\/h2>\n\n\n\n<p class=\"has-text-align-left\">We specialize in building workstation PCs tailored for each of our customers. The best way we&#8217;ve found to accomplish that is to speak with you directly. 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He and his team design, fabricate and deploy optical instruments for clinical applications.<\/p>\n","protected":false},"author":142,"featured_media":10912,"menu_order":0,"template":"","meta":{"_acf_changed":false,"content-type":"","classic-editor-remember":"","legacy_id":"247","redirect_url":[],"expire_date":"","alert_message":"","alert_link":[],"configure_ids":"","system_grid_title":"","system_grid_ids":""},"case_study_categories":[],"case_study_tags":[9304],"coauthors":[9026],"class_list":["post-10913","case_study","type-case_study","status-publish","has-post-thumbnail","hentry","case_study_tag-hpc"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.7 (Yoast SEO v26.7) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Case Study with Dr. Adam Glaser from the University of Washington | Puget Systems<\/title>\n<meta name=\"description\" content=\"Dr. Glaser works as a researcher in the Molecular Biophotonics Laboratory in the Department of Mechanical Engineering at the University of Washington. 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